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Volume 1, # 4 - August, 1995

Table of Contents

STATE-OF-THE-ART MANAGEMENT OF CANCER
LUNG CANCER
Epidemiology 82
  Lung Cancer 82
  Mesothelioma 82
Classification 82
  Small Cell Lung Cancer 82
  Non Small Cell Lung Cancer 83
  Mesothelioma 83
Etiology and Pathogenesis 83
  Lung Cancer 83
    Cigarette smoking 83
    Other respiratory carcinogens 84
    Molecular factors 84
  Mesothelioma 84
Presentation, Diagnosis and Staging 84
  Biomarkers 88
  Radioconjugates 90
    OncoTrac 90
    CEA-Scan 90
    131I anti-CEA-anti-carbohydrate 19-9 90
    Radiolabeled somatostatin 90
Prognosis 90
  Non Small Cell Lung Cancer 90
  Small Cell Lung Cancer 91
  Mesothelioma 91
Prevention 91
  Retinoids 91
Current Therapy 92
  Stage I and II nsclc 92
    Surgical resection 92
    Radiotherapy/chemotherapy 93
  Stage III nsclc 93
  Stage IV nsclc 94
    Vinorelbine 94
  Small Cell Lung Cancer 95
    Etoposide 95
    Combination chemotherapy 95
    High-dose chemotherapy 95
    Radiation therapy 95
    Surgery 95
  Mesothelioma 96
  Recurrent Lung Cancer 97
  Secondary Tumors 97
  Cancers Metastatic to the Lung 97
New Drugs and Allied Therapies in Development 98
  Chemotherapeutic Agents in Late Clinical Trials 98
    Gemcitabine 98
  Angiogenesis 98
  Gene Transfer/Vaccines/Monoclonal Antibodies 98
    Introgen Therapeutics 98
    PharmaGenics 98
    AntiCancer 99
    Transgene 99
    Medarex 99
    NeoRx 99
    Protein Design Labs 100
  Cytokines/Growth Factors 100
    Interferons 100
    Interleukins 101
  Photodynamic Therapy 101
    QLT Phototherapeutics 101
  Other Novel Strategies 102
    Sugen 102
    SunPharm 102
MEETING COVERAGE
ADVANCES IN THE TREATMENT OF LUNG CANCER
From the 31st Annual Session of the American Society of Clinical Oncology
Los Angeles, CA - May 20-23, 1995
New Chemotherapeutics 102
  Taxanes 102
    Docetaxel 102
    Paclitaxel 102
  Antimetabolites 110
    Gemcitabine 110
  Vinca Alkaloids 110
    Vinorelbine 110
  Topoisomerase I Inhibitors 111
    Irinotecan 111
    Topotecan 111
Chemotherapeutic Support and Enhancement 111
  Amifostine 111

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