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FUTURE ONCOLOGY
Volume 4 # 1/2 May/June 1998
State-of-the-Art in the Management of Cancer

Prostate Cancer-PART III
Current Treatment Modalities

Surgery Versus Brachytherapy

  • Radical Prostatectomy
  • Nerve-sparing (NS) prostatectomy

Radiotherapy/Brachytherapy

  • Permanent interstitial implant brachytherapy
  • High-dose-rate (HDR) temporary brachytherapy

Hormonal Therapy

Chemotherapy

  • Estramustine
  • Mitoxantrone
  • Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)

Special Mid-year Review

Overview of Oncology Trends-PART I

New Chemotherapeutics Take-Off

Topoisomerase I Inhibitors

  • Topotecan
  • Irinotecan
  • Other topo I inhibitors

Taxanes

  • Paclitaxel
  • Docetaxel
  • Other taxanes/taxoids

Other Chemotherapeutics

  • Mitoxantrone
  • Gemcitabine

Newly Approved Chemotherapeutics, New Indications and Adjunct Therapies

  • Anzemet
  • Fareston
  • Femara
  • Intron A
  • Neumega
  • Neupogen
  • Photofrin
  • Proleukin
  • Quadramet

New Chemotherapeutics Awaiting in the wings

  • Capecitabine
  • Denileukin diftitox
  • Emitefur
  • Oxaliplatin
  • Raltitrexed
  • UFT

Monoclonal Antibodies Come of Age

  • Rituxan
  • Herceptin
  • Other HER2 MAb-based agents

Radioimmunoconjugates

Prevention/Treatment of Metastasis

Matrix Metalloproteinase Inhibitors (MMPI)

  • Marimastat
  • AG3340
  • BAY 12-9566

Inhibition of Angiogenesis and Tumor Vascularization

  • Thalidomide
  • Endostatin and Angiostatin
  • Squalamine

Chemoprevention

Antiestrogens in Breast Cancer

  • Tamoxifen
  • Raloxifene
  • Other selective estrogen receptor modulators

Meeting Coverage

ADVANCES IN THE TREATMENT OF BREAST CANCER

From the 34th Annual meeting of the American Society of Clinical Oncology Los Angeles, CA; May 16-19, 1998

Antiestrogens in the Prevention of Recurrence of Early Breast Cancer

  • Expression of c-erbB2 and Antiestrogen Therapy

Treatment of Locoregional Disease

  • Use of Breast Conserving Therapy in the USA
  • Economics of Locoregional Radiotherapy in Canada

Adjuvant Chemotherapy

  • CAF versus CMF
  • Capecitabine
  • Paclitaxel

Treatment of Metastatic Breast Cancer

  • Docetaxel
  • Paclitaxel
  • Vinorelbine and Paclitaxel Combination
  • Losoxantrone
  • High-dose Chemotherapy/Stem Cell Transplantation (HCSCT) Compared with Chemotherapy Alone
  • Gemcitabine and Cisplatin Combination

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