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FUTURE ONCOLOGY
Volume 4 #10/11 February/March 1999
State-of-the-Art in the Management of Cancer

KIDNEY CANCER-PART II
Molecular Markers, Diagnosis, Staging and prognosis and Current TReatment Modalities

Major Types of Kidney Cancer

Renal Cell Carcinoma (RCC)

Urothelial Carcinoma of the Renal Pelvis, Ureter, and Calyces

Wilms' Tumor

Molecular Markers

Hereditary Markers

Markers Associated with Sporadic RCC

Diagnosis of Kidney Cancer

Staging of Kidney Cancer

Renal Cell Carcinoma

Transitional Cell Carcinoma of the Renal Pelvis and Ureter

Wilms’ Tumor

Prognosis

Current Approaches Used in the Treatment of Kidney Cancer

Surgery

Radiation Therapy

Immunotherapy

  • Recombinant IL-2
  • Combination immunotherapy
  • Tumor infiltrating lymphocytes

Chemotherapy

Chemoimmunotherapy

Treatment Approaches by Kidney Cancer Type and Stage

Renal Cell Carcinoma

  • Stage I or II RCC
  • Stage III RCC
  • Stage IV or recurrent RCC

Transitional Cell Tumor of the Renal Pelvis and Ureter

  • Localized TCC
  • Regional TCC

Wilms’ Tumor

Meeting Coverage

UPDATE ON OVARIAN CANCER

From the 90th Annual Meeting of the American Association for Cancer Research (AACR)

Philadelphia, PA, April 10-14, 1999

Genetics of Ovarian Cancer

Metastatic Disease

Angiogenesis

  • Carboxyamido-triazole (CAI)

p53

  • E1B-deleted adenovirus

HER2/neu

  • Herceptin
  • Viral E1A gene transfer
  • Conjugated anti-HER-2 antibodies

PI3K Signaling Pathway

BRCA-1 Expression and Familial Ovarian Cancer

Borderline Ovarian Cancer


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