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Future Oncology - Technology, Products, Markets, and Service Opportunities

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FUTURE ONCOLOGY - TECHNOLOGY, PRODUCTS, MARKETS, AND SERVICE OPPORTUNITIES IN THE CANCER FIELD

FUTURE ONCOLOGY
Volume 7 #1/2 August 31, 2002


Anticancer Drugs and Markets

UPDATE ON SPINDLE POISONS - PART III
NOVEL AGENTS IN DEVELOPMENT

NOVEL MICROTUBULE STABILIZING COMPOUNDS OBTAINED FROM NATURAL SOURCES-EXTRACTS, AND SEMISYNTHETIC AND SYNTHETIC ANALOGS
  • Colchicine-site Binders
    • Curacin
  • Combretastatins
    • AVE806
    • Combretastatin A-4 prodrug (CA4P)
    • Oxi-4503
  • Cryptophycins
    • LY355703
  • Discodermolide
  • Dolastatin and Analogs
    • Auristatin PHE
    • Dolastatin 10
    • ILX-651
    • Symplostatin 1
    • TZT-1027
  • Epothilones
    • BMS-247550
    • BMS-310705
    • EPO906
    • KOS-862
    • ZK-EPO
  • Eleutherobin
  • FR182877
  • Halichondrin B
    • E7389
  • Halimide
    • NPI-2352 and NPI-2358
  • Hemiasterlins
    • HTI-286
  • Laulimalide
  • Maytansinoids
    • Bivatuzumab mertansine
    • Cantuzumab mertansine
    • huN901-DM1/BB-10901TAP
    • MLN591DM1
    • My9-6-DM1
    • Trastuzumab-DM1
  • PC-SPES
  • Peloruside A
  • Resveratrol
  • S-allylmercaptocysteine (SAMC)
  • Spongistatins
  • Vitilevuamide
MOLECULAR MOTOR-KINESINS
  • SB-715992
DESIGNED COLCHICINE-SITE BINDERS
  • A-289099
  • A-293620/A-318315
  • ABT-751/E7010
  • D-24851/D-64131
  • ZD6126
OTHER NOVEL SPINDLE POISONS
  • 2-Methoxyestradiol (2-ME2)
  • Bezimidazole Carbamates
    • ANG 600 series
    • Mebendazole
  • CP248/CP461
  • HMN-214
  • R440
  • SDX-103
  • T67/T607

LIST OF EXHIBITS

Exhibit 1 - Novel Spindle Poisons and Formulations


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